Melanotan Mixing & Dosage Protocols

Melanotan II — Research Dosage Guidance
Reconstitution (Mixing)

  • Add 2 ml Bacteriostatic Water to the vial
  • Roll gently between palms (do not shake)
  • Store reconstituted vial in the refrigerator (2–8 °C)

Concentration Calculation

10 mg ÷ 2 ml = 5 mg/ml

Every 10 units (0.1 ml) = 0.5 mg (500 mcg)

Core Dosage Guidelines

For pigmentation, libido enhancement, and photoprotection research

Loading Phase

Dose: 250–500 mcg daily

Duration: Until desired pigmentation is achieved (typically 7–14 days)

Maintenance Phase

Dose: 250–500 mcg

Frequency: 2–3× per week

Administration: Subcutaneous (abdomen or thigh)
Optional timing: Evening dosing may reduce nausea or flushing

Syringe Measurement Guide
Dose    Volume (ml)    Insulin Units
250 mcg    0.05 ml    5 units
500 mcg    0.10 ml    10 units
1 mg    0.20 ml    20 units

Reference: Every 10 units (0.1 ml) = 500 mcg Melanotan II

Targeted Research Protocols (Different Situations)
1.⁠ ⁠Gradual Pigmentation / First-Time Research

  • (Minimizing side effects, controlled melanin activation)
  • Dose: 250 mcg
  • Frequency: Once daily
  • Duration: 10–14 days
  • Maintenance: 250 mcg 2× weekly
  • Notes: Preferred for sensitive research models

2.⁠ ⁠Rapid Pigmentation Development

  • (Short-term melanin induction models)
  • Dose: 500 mcg
  • Frequency: Daily
  • Duration: 7–10 days
  • Maintenance: 500 mcg 2× weekly
  • Notes: Monitor for flushing and nausea

3.⁠ ⁠Photoprotection & UV-Resilience Research

  • (Skin resilience, UV response modulation)
  • Dose: 250–500 mcg
  • Frequency: 2–3× weekly
  • Duration: 6–8 weeks
  • Notes: Pigmentation may deepen gradually

4.⁠ ⁠Libido & Energy Pathway Research

  • (α-MSH–related libido and mood effects)
  • Dose: 250–500 mcg
  • Frequency: 2–3× weekly
  • Timing: Evening dosing preferred
  • Duration: 4–6 weeks
  • Notes: Lower doses often sufficient

5.⁠ ⁠Maintenance / Long-Term Tone Preservation

  • Dose: 250 mcg
  • Frequency: Once weekly
  • Duration: As required after full cycle
  • Notes: Helps sustain pigmentation with minimal exposure

Cycle Duration

  • Initial pigmentation: ~1–2 weeks of daily dosing
  • Maintenance: 2–3 injections per week
  • Typical research cycle: 6–8 weeks
  • Breaks: Recommended between cycles

Key Research Benefits

  • Stimulates melanin production for gradual, natural pigmentation
  • Supports UV protection and skin resilience
  • May enhance libido and energy pathways
  • Promotes mood and body-confidence signaling via α-MSH activation

Important Notes

Always use sterile needles and alcohol swabs

Do not reuse or share needles

Store reconstituted vial at 2–8 °C

For research use only

Possible dose-dependent effects include:

Temporary nausea or flushing

Darkening of freckles or moles