Retatrutide Mixing & Dosage Protocols
(Triple GLP-1 / GIP / Glucagon Receptor Agonist for Metabolic & Weight-Loss Research)
Reconstitution (Mixing)
- Add 3 ml Bacteriostatic Water to the vial.
- Roll gently between your palms (do not shake).
- Store in the refrigerator after mixing.
Concentration Calculation
30 mg ÷ 3 ml = 10 mg per ml
Every 10 units (0.1 ml) = 1 mg Retatrutide
Dosage Guidelines
For metabolic enhancement, glucose regulation, and fat-reduction research:
- Start: 1 mg (10 units) once per week to assess tolerance
-
Titration:
- Weeks 3–4 → 2 mg (20 units) weekly
- Weeks 5–6 → 4 mg (40 units) weekly
- Weeks 7+ → 6 mg (60 units) weekly or as tolerated
- Administration: Subcutaneous injection (abdomen, thigh, or upper arm)
- Frequency: Once weekly on the same day each week
Biopeptics recommendation:
Always start by assessing tolerance with a micro-dose of 1 mg, and stay on the lowest effective dose for as long as possible. Some individuals may not need to increase their dosage at all - only adjust the dose if truly necessary, and do so in very small increments.
Key Benefits:
- Potent triple-pathway action on GLP-1 / GIP / Glucagon receptors
- Enhances energy expenditure, fat oxidation, and metabolic flexibility
- Improves appetite control and glucose homeostasis
- Supports cardiovascular health and lean-mass preservation
Syringe Measurement Guide
|
Dose |
Volume (ml) |
Insulin Units (U-100 Syringe) |
|
1 mg |
0.10 ml |
10 units |
|
2 mg |
0.20 ml |
20 units |
|
4 mg |
0.40 ml |
40 units |
|
6 mg |
0.60 ml |
60 units |
Each 10 units (0.1 ml) = 1 mg Retatrutide.
Cycle Duration
Typical cycle: 12 – 24 weeks, depending on research goals.
Maintenance: Continue weekly dosing at the lowest effective level for ongoing metabolic support.
Important Notes
- Always use sterile needles and alcohol swabs.
- Do not reuse or share needles.
- Store reconstituted vial in the refrigerator (2 – 8 °C).
- For research use only.
- Possible transient effects: mild nausea, headache, fatigue, or injection-site redness.
