Tirzepatode Mixing & Dosage Protocols

(Dual GLP-1 & GIP Receptor Agonist for Advanced Weight Management Research)

Reconstitution (Mixing)

  • Add 3 ml Bacteriostatic Water to the vial.
  • Roll gently between your palms (do not shake).
  • Store in the refrigerator after mixing.

Concentration Calculation

30 mg ÷ 3 ml = 10 mg per ml

Every 10 units (0.1 ml) = 1 mg 

Dosage Guidelines

For appetite regulation, metabolic balance, and weight-loss research:

  • Starting dose: 2.5 mg (≈ 25 units) once per week
  • Titration schedule:
    • Weeks 3–4 → 5 mg (50 units) weekly
    • Weeks 5–6 → 7.5 mg (75 units) weekly
    • Weeks 7–8 → 10 mg (100 units) weekly
    • Continue upward only if well-tolerated and required for study outcomes
  • Administration: Subcutaneous injection (abdomen, thigh, or upper arm)
  • Frequency: Once weekly on the same day

Biopeptics recommendation:

Always start by assessing tolerance with a micro-dose of 2.5 mg, and stay on the lowest effective dose for as long as possible. Some individuals may not need to increase their dosage at all - only adjust the dose if truly necessary, and do so in very small increments.

Key Benefits:

  • Enhances insulin sensitivity and metabolic efficiency
  • Promotes fat reduction while preserving lean mass
  • Improves appetite control, energy stability, and glucose regulation
  • Supports cardiovascular health markers in long-term research

Syringe Measurement Guide

Dose

Volume (ml)

Insulin Units (U-100 Syringe)

1 mg

0.10 ml

10 units

2.5 mg

0.25 ml

25 units

5 mg

0.50 ml

50 units

7.5 mg

0.75 ml

75 units

10 mg

1.00 ml

100 units

Each 10 units (0.1 ml) = 1 mg Tirzepatide.

Cycle Duration

Typical research cycle: 12–24 weeks for measurable outcomes.

Maintenance: Continue lowest tolerated dose weekly for ongoing metabolic support.

Important Notes

  • Always use sterile needles and alcohol swabs.
  • Do not reuse or share needles.
  • Store reconstituted vial in the refrigerator (2 – 8 °C).
  • For research use only.
  • Possible transient effects: mild nausea, fatigue, or injection-site redness; reduce dose if discomfort persists.