Glutathione - 1500 mg (Tripeptide Antioxidant Peptide)

1. Master Antioxidant & Cellular Defense

Glutathione neutralizes reactive oxygen species (ROS) and supports enzymes involved in detoxification. In research models, it:

• Protects DNA and cell membranes from oxidative damage
  
• Regenerates other antioxidants (vitamin C, vitamin E)
  
• Supports liver-phase detoxification pathways
  
• Reduces inflammatory signaling at a cellular level
  

Its strong ROS-scavenging activity makes it valuable in studies examining oxidative stress, metabolic dysfunction, and cellular aging.

2. Skin Brightening & Pigmentation Pathways

Research indicates Glutathione influences melanin synthesis by:

• Inhibiting tyrosinase (the key pigment-producing enzyme)
  
• Shifting melanin production from eumelanin (dark pigment) to pheomelanin (lighter pigment)
  
• Supporting reduction of oxidative stress within melanocytes
  

These mechanisms make it a popular molecule in pigmentation, aesthetic, and dermatology research.

3. Immune Regulation & Inflammation Control

Glutathione contributes to immune balance by:

• Supporting lymphocyte proliferation
  
• Reducing pro-inflammatory cytokine activity
  
• Enhancing cellular resilience in models of infection or chronic inflammation
  

Its immune-modulating properties are frequently explored in immunology and systemic-inflammation studies.

4. Mitochondrial Function & Detoxification

Within mitochondria, Glutathione:

• Supports ATP production
  
• Protects mitochondrial DNA
  
• Enhances detoxification of metabolic byproducts
  

This makes it a key molecule in longevity, metabolic, and neuroprotective research models.

• Oxidative stress and detoxification studies
  
• Dermatology and pigmentation research
  
• Immune modulation models
  
• Liver and metabolic-health research
  
• Mitochondrial function and cellular aging studies
  

Glutathione – 1500 mg Lyophilized Peptide Powder

Glutathione (GSH) — Research Dosage Guidance
Reconstitution (Mixing)

• Add 3.0 ml Bacteriostatic Water to the vial
• Final concentration: 500 mg per ml
• Roll gently to dissolve (do not shake)
• Store in the refrigerator (2–8 °C)

Concentration Calculation

1,500 mg ÷ 3 ml = 500 mg/ml

Every 1 insulin unit (0.01 ml) = 5 mg Glutathione

Core Dosage Guidelines (Subcutaneous)

• Target weekly total: 1,500 mg
• Injection frequency: 3× weekly

Standard Dosing Schedule

Weeks 1–2 (Initiation)

300 mg per injection

0.60 ml (60 units)

900 mg per week

Weeks 3–12 (Full Protocol)

500 mg per injection

1.0 ml (100 units)

1,500 mg per week

Optional Weeks 12–16

500 mg per injection

1.0 ml (100 units)

1,500 mg per week

Example injection days: Monday – Wednesday – Friday

Dose Conversion Table
Dose    mL    Units
300 mg    0.60 ml    60 units
500 mg    1.0 ml    100 units

Targeted Research Protocols (Different Situations)
1.⁠ ⁠Antioxidant & General Wellness Research

• (Oxidative stress reduction, cellular protection models)
• Dose: 250–300 mg
• Frequency: 2–3× weekly
• Weekly total: 500–900 mg
• Duration: 6–10 weeks
• Notes: Suitable for maintenance or first-time research models

2.⁠ ⁠Immune Support & Inflammation Research

• (Immune modulation, recovery support)
• Dose: 300–500 mg
• Frequency: 3× weekly
• Weekly total: 900–1,500 mg
• Duration: 8–12 weeks
• Notes: Aligns with standard protocol

3.⁠ ⁠Liver Support & Detoxification Research

• (Hepatic stress, toxin exposure models)
• Dose: 500 mg
• Frequency: 3× weekly
• Weekly total: 1,500 mg
• Duration: 8–16 weeks
• Notes: Ensure adequate hydration in research models

4.⁠ ⁠Intensive Oxidative Stress / Recovery Models

• (Post-illness, high metabolic stress, advanced research)
• Dose: 500 mg
• Frequency: 3× weekly
• Weekly total: 1,500 mg
• Duration: 12–16 weeks
• Notes: Advanced protocol only

5.⁠ ⁠Skin, Pigmentation & Cellular Aging Research

• (Melanin modulation, skin clarity, anti-aging pathways)
• Dose: 300–500 mg
• Frequency: 2–3× weekly
• Weekly total: 600–1,500 mg
• Duration: 8–12 weeks
• Notes: Gradual onset protocols preferred

6.⁠ ⁠Maintenance / Long-Term Support Research

• Dose: 250–300 mg
• Frequency: 1–2× weekly
• Weekly total: 250–600 mg
• Duration: Ongoing after a full cycle

Vial Usage

• Each vial contains 1,500 mg total
• 3 × 500 mg doses per vial
• 1 vial = 1 full week during full protocol

Reconstitution Steps

• Draw 3.0 ml bacteriostatic water
• Inject slowly down the vial wall to prevent foaming
• Swirl gently until fully dissolved
• Refrigerate at 2–8 °C immediately
• Do not freeze once reconstituted
• Solution should be clear to pale yellow

Cycle Duration

Standard protocol: 8–12 weeks

Optional extension: Up to 16 weeks

Research Use Disclaimer

For research and educational purposes only.
Not intended to diagnose, treat, or cure any condition.

Glutathione Who Should Use With Caution or Avoid (Research Contexts)

Glutathione is a central antioxidant involved in cellular redox balance and detoxification pathways. Use caution or avoid in the following research contexts:

Active cancer or tumor-bearing models (may influence cellular survival and treatment-response pathways)

Severe asthma or hypersensitivity-prone models (rare sensitivity reactions reported)

Known sulfur sensitivity (thiol-containing compound; mild reactivity possible)

Uncontrolled detoxification or hepatic-function models (may alter liver enzyme or oxidative-stress markers)

Glutathione is a powerful intracellular antioxidant central to research on detoxification, skin brightening, immune support, and cellular longevity. Its redox-balancing properties make it essential in oxidative stress and metabolic studies. Side effects are typically mild and self-limiting, often related to detoxification shifts or local injection irritation. Proper dilution and slow administration help ensure predictable and consistent outcomes in research settings.