Semax - 10 mg (Neuroregenerative Heptapeptide)

1. BDNF & Neurotrophin Activation -Brain Growth and Repair

Semax increases BDNF, NGF (Nerve Growth Factor), and TrkB receptor signaling, all of which support:

• Neuronal growth and survival
• Synaptic plasticity and learning capacity
• Enhanced cognitive function and memory retention
• Recovery of neurons after stress or ischemic damage

This BDNF-mediated response is central to Semax’s role in neurorestoration and performance enhancement research.

2. Modulation of Dopamine & Serotonin Systems

Semax regulates neurotransmitter activity in key brain regions, helping to balance dopamine and serotonin levels. This contributes to:

• Improved motivation, focus, and alertness
• Mood stabilization and emotional regulation
• Reduced cognitive fatigue under stress conditions

Its mechanism makes Semax valuable in neurotransmission and mood-balance studies.

3. Protection Against Oxidative & Ischemic Stress

In preclinical research, Semax has shown strong neuroprotective effects by:

• Reducing oxidative stress and free-radical damage
• Improving cerebral blood flow and oxygen utilization
• Supporting mitochondrial stability under hypoxic conditions

These effects make it a key molecule for stroke recovery, neurodegenerative, and longevity-related research.

4. Cognitive Enhancement & Learning Support

By upregulating neuroplasticity genes and improving acetylcholine balance, Semax supports:

• Sharper memory recall
• Enhanced learning ability and concentration
• Mental endurance and resilience during cognitive load

Its multifaceted action gives it a strong research profile for performance and neuroplasticity enhancement.

• Neuroprotection and brain-injury recovery studies
• Learning, memory, and focus optimization research
• Mood and stress-response modulation
• BDNF and neurotrophic-factor signaling studies
• Anti-fatigue and cognitive-performance investigations

Semax -10 mg Lyophilized Peptide Powder

Semax (10 mg) — Research Dosage Guidance
Reconstitution (Mixing)

• Add 2 ml Bacteriostatic Water to the vial
• Roll gently between palms (do not shake)
• Store reconstituted vial in the refrigerator (2–8 °C)

Concentration Calculation

10 mg ÷ 2 ml = 5 mg per ml

Every 10 insulin units (0.1 ml) = 0.5 mg (500 mcg)

Core Dosage Guidelines

• For cognitive support, focus, neuroprotection, and stress-adaptation research
• General cognitive use: 250–500 mcg per day
• Enhanced focus / mood support: 500 mcg – 1 mg per day
• Neuro-repair / post-stress / stroke-model research: 1 mg twice daily
• Administration: Subcutaneous injection (abdomen, thigh, or upper arm)
• Note: Intranasal delivery is studied in literature, but Biopeptics supplies the injectable format for precision, consistency, and stability in research settings.

Syringe Measurement Guide
Dose    Volume    Insulin Units
250 mcg    0.05 ml    5 units
500 mcg    0.10 ml    10 units
1 mg    0.20 ml    20 units

Reference: Every 10 units (0.1 ml) = 500 mcg Semax

Targeted Research Protocols (Different Situations)
1.⁠ ⁠Daily Cognitive Performance & Mental Clarity

• (Focus, productivity, mental stamina)
• Dose: 250–500 mcg
• Frequency: Once daily
• Timing: Morning or early afternoon
• Duration: 10–14 days
• Notes: Suitable for routine cognitive research

2.⁠ ⁠Enhanced Focus, Mood & Stress Resilience

• (Executive function, emotional regulation models)
• Dose: 500 mcg – 1 mg
• Frequency: Once daily
• Timing: Morning preferred
• Duration: 10–20 days
• Notes: Avoid late evening dosing due to alertness effects

3.⁠ ⁠Neuroprotection & Recovery Research

• (Post-stress, post-injury, ischemic or neuro-repair models)
• Dose: 1 mg
• Frequency: Twice daily
• Timing: Morning + early afternoon
• Duration: 10–20 days
• Notes: Advanced protocol for intensive research use

4.⁠ ⁠Anxiety & Stress-Adaptation Research

• (HPA-axis modulation, resilience studies)
• Dose: 250–500 mcg
• Frequency: Once daily
• Timing: Morning
• Duration: 10–15 days
• Notes: Lower doses often sufficient

5.⁠ ⁠Maintenance / Intermittent Cognitive Support

• Dose: 250 mcg
• Frequency: 3–5 days per week
• Duration: As needed after a full cycle
• Notes: Helps maintain benefits with reduced exposure

Cycle Duration

• Typical cycle: 10–20 days
• Off period: 1–2 weeks
• Repeat cycles: May be repeated or used intermittently depending on research goals

Key Research Benefits

• Supports learning, memory, and attention pathways
• Promotes neuroprotection and synaptic plasticity
• Enhances stress resilience and mental clarity
• May support recovery following neurological stressors
• Non-hormonal peptide with a favorable research safety profile

Important Notes

Always use sterile needles and alcohol swabs

Do not reuse or share needles

Store reconstituted peptide at 2–8 °C

For research use only

Semax is a neuroactive peptide that modulates neurotransmission, neurotrophic signaling, and cognitive-performance pathways. Use caution or avoid in the following research contexts:

Pregnancy or lactation models (no safety data available)

Severe anxiety-prone or bipolar-spectrum models (neurostimulatory effects may heighten activation)

Epilepsy or seizure-prone models (altered excitatory neurotransmission may affect thresholds)

Uncontrolled hypertension models (monitor for mild, transient blood-pressure changes)

Late-evening administration in sleep or circadian studies (may disrupt sleep architecture)

Concurrent use with stimulants or multiple nootropic agents (cumulative dopaminergic or excitatory load may increase restlessness)

Semax is a neuroprotective peptide that supports cognitive performance, focus, and neural repair through BDNF and neurotransmitter modulation. It is well tolerated, with the most common side effects being mild headache, nasal irritation, restlessness, or small itchy welts. Symptoms are transient and dose-related, often resolving with dilution adjustment or morning administration for optimal focus and minimal sleep disruption.